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mitochondrial dysfunction
Tradução de "mitochondrial dysfunction" em chinês
线粒体功能障碍
Hence, it is not surprising that treatment of mitochondrial dysfunction and development of mitochondrion-targeted therapeutics have become a primary focus of scientific research.
因此，治疗线粒体功能障碍以及开发定位于线粒体的疗法已成为科学研究的首要重点不足为奇。
The oxidative stress may be caused by mitochondrial dysfunction, by activation of immune cells, such as macrophages and neutrophils, by acute exposure to an external agent, such as ionizing radiation or a cytotoxic chemotherapeutic agent (e.g., doxorubicin), by trauma or other acute tissue injury, by ischemia/reperfusion, by poor circulation or anemia, by localized or systemic hypoxia or hyperoxia, by elevated levels of inflammatory cytokines and other inflammation-related proteins, and/or by other abnormal physiological states, such as hyperglycemia or hypoglycemia.
氧化应激可由以下引起：线粒体功能障碍，例如巨噬细胞和嗜中性粒细胞的免疫细胞的活化；短暂暴露于外部因素 （external agent） ，例如电离辐射或细胞毒性化学治疗剂 （ 例如，多柔比星 ） ；创伤或其它急性组织损伤；局部缺血/ 再灌注；差的循环或贫血；局部或全身性的缺氧或氧过多；升高水平的炎性细胞因子和其它炎症相关蛋白；和/ 或其它异常生理状态，例如高血糖或低血糖。
NRTI exposure has been associated with mitochondrial dysfunction in the first few months of life even in uninfected infants (5, 45).
暴露于 核苷类逆转录酶抑制剂 与 婴儿 （ 即使是未被感染的婴儿 ） 最初 几个月的线粒体功能障碍有关 。
Mitochondria is responsible for signaling inside the cell, regulates process of apoptosis, cellular proliferation, and cell death. Abnormal death of cell due to mitochondrial dysfunction can affect the function of entire organ.
线粒体负责细胞内信号，调节细胞凋亡程序，细胞增殖及细胞死亡。由于线粒体功能障碍而引发的细胞异常死亡，能影响整个器官的功能。
It is found that 3-nitropropionic acid is a mitochondrial toxin and produces striatal alterations in rats similar to those observed in the brain of Huntington's disease patients, and administration of the cannabinoid receptor agonist WIN55212-2 to rats for six consecutive days, before the 3-NPA injection, exerted preventive effects on all alterations elicited by the toxin, like mitochondrial dysfunction and lipid peroxidation, by activation of the CB1 receptor.
研究发现β-硝基丙酸是一种线粒体毒素并且在大鼠模型中产生类似于在亨廷顿氏病患者的脑中观察到的纹状体改变，并且在大鼠注射3-NPA之前连续六天施用大麻素受体激动剂WIN55212-2，通过激活CB1受体，对毒素引起如线粒体功能障碍和脂质过氧化，发挥预防作用。
Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment.
抗磷脂综合征中的线粒体功能障碍：疾病发病机制的启示和辅酶Q10治疗的效应
What they discovered was the aforementioned mitochondrial dysfunction that lead to problems with energy.
他们发现的正是前面提到的导致能量供应问题的线粒体功能异常。
The stated rationale for the study is that airborne pollutants can cause mitochondrial dysfunction and neuronal toxicity in exposed populations.
对这项研究陈述的理由，是空飘污染物造成暴露人口的线粒体紊乱和神经源中毒。
Besides these two non-syndromic optic neuropathies, optic atrophy is a prominent feature in many other neurodegenerative diseases that are now recognized as due to primary mitochondrial dysfunction.
目前认为，包括这两种非视神经病变综合征的疾病，视神经萎缩也是其它一些因线粒体功能障碍导致的神经变性疾病的突出特征。
Since the study found a link between sirtuins and energy utilization, the researchers concluded that resveratrol may be helpful in the prevention and treatment of certain metabolic disorders, especially those related to mitochondrial dysfunction, such as Alzheimer's and Parkinson's disease-two neurodegenerative conditions that become more prevalent with aging.
由于该研究发现沉默调节蛋白和能量利用率之间的一个联结，研究人员得出结论：白藜芦醇可能有助于预防和治疗某些代谢疾病，特别是那些与线粒体功能障碍有关者，如阿尔茨海默氏症和帕金森氏症 - 两种随老化变得更加普遍的神经变性状况。
to mitochondrial dysfunction and injury of the nervous tissue (polyneuropathy, Alzheimer's disease, multiple sclerosis and other cognitive disorders),
到线粒体能障碍和损伤的神经组织（多发性神经病、阿耳茨海默氏病、多发性硬化和其他的认知障碍 ） ，
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