The commercially available reverse transcriptases produced by Promega are quoted by their manuals as having error rates in the range of 1 in 17,000 bases for AMV and 1 in 30,000 bases for M-MLV.
Het commercieel beschikbare reverse-transcriptase van Promega maakt bij 1 op de 17.000 basen voor AMV een fout en 1 op 30.000 basen voor M-MLV.
Reverse transcriptases were discovered by Howard Temin at the University of Wisconsin-Madison in RSV virions and independently isolated by David Baltimore in 1970 at MIT from two RNA tumour viruses: R-MLV and again RSV.
Reverse-transcriptasen zijn ontdekt door Howard Temin op de University of Wisconsin-Madison in RSV virions en onafhankelijk van hem in 1970 geïsoleerd door David Baltimore aan de Massachusetts Institute of Technology uit de twee RNA tumor virussen: R-MLV en opnieuw bij RSV.
This is the family of reverse transcriptases, which includes eukaryotic telomerases and the reverse transcriptases found in retroviruses.
Naïve patients also received nucleoside reverse transcriptase inhibitors.
De naïeve patiënten kregen ook nucleoside reverse transcriptase inhibitors.
They were exposed to lethal concentrations of non-nucleoside reverse transcriptase inhibitors.
Ze werden blootgesteld aan dodelijke hoeveelheden... non-nucleoside omgekeerde transcriptase afremmers.
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