In answering this question, one cannot do without examples.
A modern-day motorcyclist's kit cannot do without the modern mobile.
Today we feel we cannot do without this endeavour that brings us together.
Transportation is one aspect we cannot do without in this day and age.
They cannot do without camels in this country.
Besides, men cannot do without women.
We cannot do without it at home and in the office.
No podemos prescindir de él en casa y en el trabajo.
The ability to read is a skill that a school cannot do without.
La capacidad de leer es una habilidad que una escuela no puede prescindir.
The regime of a given class cannot do without its own intellectuals.
El régimen de una clase determinada no puede prescindir de sus propios intelectuales.
At the same time, capitalism-imperialism cannot do without patriarchy.
Al mismo tiempo, el capitalismo-imperialismo no puede prescindir del patriarcado.
But sleep is something you truly cannot do without.
Pero el sueño es algo que realmente no puede prescindir.
In our view, one cannot do without the other.
Para nosotros, uno no puede prescindir del otro.
As you see, we cannot do without you.
Como veis, no podemos prescindir de vos.