Without an opposable thumb, using tools would be extremely difficult.
His loathsome attitude made collaborating on the project extremely difficult.
The question of access to origins was extremely difficult to resolve.
I understand coming here for the first time is extremely difficult.
The die-hard nature of these weeds makes them extremely difficult to eradicate.
Adhesive capsulitis can make simple tasks like dressing extremely difficult.
Every step toward me must have been extremely difficult to take.
Chacun de ses pas vers moi a dû être très difficile à effectuer.
Decoding the files is often extremely difficult for law enforcement agencies.
Il est souvent extrêmement difficile pour la police de décoder les fichiers.
Estimating the importance of all known sources is therefore extremely difficult.
Estimer l'importance de toutes les sources connues est donc extrêmement difficile.
The spiral of hatred and revenge is extremely difficult to interrupt.
La spirale de haine et de revanche est extrêmement difficile à interrompre.
That situation makes protection of and access to civilians extremely difficult.
Cette situation rend extrêmement difficile l'accès aux civils et leur protection.
However, staying in ignorance is extremely difficult and even painful.
Cependant, rester dans l'ignorance est extrêmement difficile et même douloureux.
In this extremely difficult context, young people are not spared.
Dans ce contexte extrêmement difficile, les jeunes ne sont pas épargnés.