It is up to the project manager to inform the team of these changes.
Several elements of these changes have already been mentioned here today.
The clinical relevance of these changes has not been established.
Some of these changes deal with completely vain and unnecessary things.
The likelihood of these changes was assessed by the initiating department.
La probabilité de ces changements a été évaluée par l'autorité responsable.
Some of these changes will have value for the larger society.
Certains de ces changements seront utiles à l'ensemble de la société.
We must consider the legal effect of these changes on our operations.
Nous devons prendre en compte l'impact juridique de ces changements sur nos opérations.
Yet the nature of these changes have taken many by surprise.
Pourtant, la nature de ces changements en a surpris plus d'un.
Oracle has already delivered multiple updates for most of these changes.
Oracle a livré plusieurs mises à jour pour la plupart de ces changements.
Nine of these changes had a potential impact on inhibitor formation.
Neuf de ces changements ont eu une incidence sur la formation d'inhibiteurs.
Your existing project won't even open because of these changes.
Votre projet existant ne s'ouvrira même pas en raison de ces changements.
Work is being undertaken on assessing the implications of these changes.
Des travaux sont en cours pour évaluer les effets de ces changements.
This means that the full impact of these changes cannot be determined.
Il est donc impossible de déterminer entièrement l'incidence de ces changements.